AU  - Faust, Travis E.
AU  - Devlin, Benjamin A.
AU  - Farhy-Tselnicker, Isabella
AU  - Ferro, Austin
AU  - Postolache, Maggie
AU  - Xin, Wendy
TI  - Glial Control of Cortical Neuronal Circuit Maturation and Plasticity
PT  - JOURNAL ARTICLE
DP  - 2024 Oct 02 
TA  - The Journal of Neuroscience 
VI  - 44 
IP  - 40 
4099 - http://www.jneurosci.org/content/44/40/e1208242024.abstract 
4100 - http://www.jneurosci.org/content/44/40/e1208242024.full 
SO - J. Neurosci. 2024 Oct 02; 44(40)
AID  - 10.1523/JNEUROSCI.1208-24.2024 [doi] 
AB  - The brain is a highly adaptable organ that is molded by experience throughout life. Although the field of neuroscience has historically focused on intrinsic neuronal mechanisms of plasticity, there is growing evidence that multiple glial populations regulate the timing and extent of neuronal plasticity, particularly over the course of development. This review highlights recent discoveries on the role of glial cells in the establishment of cortical circuits and the regulation of experience-dependent neuronal plasticity during critical periods of neurodevelopment. These studies provide strong evidence that neuronal circuit maturation and plasticity are non-cell autonomous processes that require both glial–neuronal and glial–glial cross talk to proceed. We conclude by discussing open questions that will continue to guide research in this nascent field.