RT Journal
A1 Faust, Travis E.
A1 Devlin, Benjamin A.
A1 Farhy-Tselnicker, Isabella
A1 Ferro, Austin
A1 Postolache, Maggie
A1 Xin, Wendy
T1 Glial Control of Cortical Neuronal Circuit Maturation and Plasticity
JF The Journal of Neuroscience 
JO The Journal of Neuroscience 
YR 2024 
FD October 02 
VO 44 
IS 40 
DO 10.1523/JNEUROSCI.1208-24.2024 
UL http://www.jneurosci.org/content/44/40/e1208242024.abstract 
AB The brain is a highly adaptable organ that is molded by experience throughout life. Although the field of neuroscience has historically focused on intrinsic neuronal mechanisms of plasticity, there is growing evidence that multiple glial populations regulate the timing and extent of neuronal plasticity, particularly over the course of development. This review highlights recent discoveries on the role of glial cells in the establishment of cortical circuits and the regulation of experience-dependent neuronal plasticity during critical periods of neurodevelopment. These studies provide strong evidence that neuronal circuit maturation and plasticity are non-cell autonomous processes that require both glial–neuronal and glial–glial cross talk to proceed. We conclude by discussing open questions that will continue to guide research in this nascent field.