Role of the Amygdala in the Coordination of Behavioral, Neuroendocrine, and Prefrontal Cortical Monoamine Responses to Psychological Stress in the Rat

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Fig. 7.
Fig. 7.

Effect of post-training amygdala lesions on neurochemical indices of the stress response in the m-PFC. A shows effect of post-training amygdala lesions on stress-induced DA utilization in the m-PFC. ***, Statistically significant difference versus the sham/no stress group,p < 0.001; ++++, statistically significant difference versus the sham/stress group, p < 0.0001. Bshows effect of post-training amygdala lesions on stress-induced 5-HT utilization and NE metabolism in the m-PFC. Animals were subjected to bilateral sham (SHAM) or excitotoxic lesions of the amygdala (AMYG-) 5 d after training. STRESS andNO STRESS indicate experimental conditions in which animals were or were not exposed to shock during conditioning, respectively. **, Statistically significant difference versus the sham/no stress group, p < 0.01; *, statistically significant difference versus the sham/no stress group, p < 0.05; +++, statistically significant difference versus the sham/stress group,p < 0.001; ++, statistically significant difference versus the sham/stress group, p < 0.01. Numbers inparenthesis indicate number of animals in each group.

  1. The Journal of Neuroscience vol. 16 no. 15 4787-4798
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