Consequences of Trisomy 16 for Mouse Brain Development: Corticogenesis in a Model of Down Syndrome

Table 2.

Cross-sectional area (mm2)

Euploid Ts16 % Difference
VZ 0.32  ± 0.08 0.28  ± 0.08* 12
CP 0.34  ± 0.09 0.18  ± 0.01** 48
Pallium 1.26  ± 0.06 0.87  ± 0.02*** 31
  • Mean values ± SEM of the VZ, CP, and entire pallium in fetal control and Ts16 mice (n = 5, each group) in parasagittal sections at E16. *p < 0.005; **p < 0.0001; ***p < 0.00001.

  1. The Journal of Neuroscience vol. 16 no. 19 6175-6182
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