Fig. 5.
Histochemical detection of astrocyte nuclei with gfa2-nlacZ transgenic mice. a, Central lobule of cerebellum from nlacZ transgenic mouse (control) treated with GCV at P3. b, Central lobule of cerebellum from nlacZ-TK double transgenic mouse (experimental) treated with GCV at P3. Note the overall smaller size of the folia, the disorganization of the nuclei in the Purkinje cell layer, and the decrease in nlacZ-stained nuclei.CL, Central lobule; scale bar, 100 μm.
