Restriction in Cell Fates of Developing Spinal Cord Cells Transplanted to Neural Crest Pathways

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Fig. 2.
Fig. 2.

Distribution of transplanted dorsal cells within a host embryo. A, Camera lucida reconstruction of the distribution of st 28 dorsal quail cells 8 d after transplantation into a st 17 host embryo. This composite drawing shows dorsal cells (indicated by dots) found within one segment of the host embryo. Donor cells are located in the DRG, sympathetic ganglia, peripheral nerves, and muscle (total number 6932 quail cells, not including melanocytes). All sections inB–F were stained with QC/PN.B, Transplanted dorsal cells within the dorsal root have elongated nuclei characteristic of differentiated Schwann cells (compare with E andF). C, Donor cells within the DRG include neurons (solid arrows), satellite cells, and Schwann cells (arrowheads). D, Donor cells in a sympathetic ganglion. E, Most donor cells within peripheral nerves are Schwann cells. F, Schwann cells in a normal st 40 quail peripheral nerve. Scale bars:A, 100 μm; B, 25 μm;C, D, 50 μm; E,F, 15 μm.

  1. The Journal of Neuroscience vol. 16 no. 23 7638-7648
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