Fig. 5.
Activation of postsynaptic receptors by photo-uncaging of (in μm): 150 CNB-glutamate, 300 GABA, and 400 carbamyl choline. A, Glutamate receptor-mediated currents from a P22 pyramidal cell. In most tested neurons a large fraction of the glutamate response was carried by NMDA receptors. Glutamate receptor-gated currents were completely suppressed by 20 μmd-APV and 50 μm CNQX.B, GABAA receptor-mediated response from a P20 pyramidal cell. GABAA receptor-mediated currents were abolished by 50 μm picrotoxin (PTX). C, Uncaging of CNB-carbamylcholine evoked inward currents that were completely blocked by 50–100 mm DHβE.
