Input Summation by Cultured Pyramidal Neurons Is Linear and Position-Independent

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Fig. 3.
Fig. 3.

Linearity of summation is independent of intrapipette distance and response amplitude. A, Percent linearity of the summation of two inputs in all spatial configurations as a function of distance between the pipettes. Distance was measured as the shortest length along the neuron between the two inputs.Dashed line indicates linearity. No systematic correlation is observed. B, Percent linearity of the summation of two inputs as a function of combined peak amplitude. No significant deviation from linearity is seen. Each pointrepresents a single experiment. More than one experiment may be performed on a given cell in either different positions or amplitudes. These data include 75 different experiments on 40 different cells and are the same data as those plotted in Figure 2.

  1. The Journal of Neuroscience vol. 18 no. 1 10-15
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