Identification, Localization, and Modulation of Neural Networks for Walking in the Mudpuppy (Necturus Maculatus) Spinal Cord

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Fig. 8.
Fig. 8.

Resetting the walking-like rhythm by dorsal root stimulation. A, Examples of raw recordings of the flexor EMG showing the measurement of cycle duration and the effects of stimulation on the cycle duration. A train of 6 pulses of 40 Hz at 1.2× the motor threshold intensity was delivered to the C3 dorsal root at times indicated by arrows. The cycle duration of the disturbed step (During) was either shortened (top trace) or prolonged (bottom trace) depending on the timing of stimulation. The cycle durations of the steps immediately before and after the disturbed step were not substantially affected.B, The cycle duration of the disturbed steps was plotted against the timing of stimulation. The effect was phase-dependent. The slope (0.912) of the best straight line fit indicates the resetting effectiveness, with 1 indicating a perfect resetting. The mean cycle durations of steps before and after the stimulated steps are also shown and are not significantly different.

  1. The Journal of Neuroscience vol. 18 no. 11 4295-4304
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