Ceramide Inhibits Inwardly Rectifying K+ Currents via a Ras- and Raf-1-Dependent Pathway in Cultured Oligodendrocytes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Fig. 9.
Fig. 9.

PMA-induced IKir inhibition in OLGs. A, Representative traces illustrating the effect of PMA in the presence of Ras Ab or in OLGs treated with antisense raf-1 ODN. B, Summarized data illustrating that PMA-inducedIKir inhibition was not prevented by Ras Ab or by antisense Raf-1 ODN (p = NS for PMA vs Ras AB + PMA and for PMA vs antisense + PMA).

  1. The Journal of Neuroscience vol. 18 no. 21 8712-8719
Responses to This Article
Be the first to respond to this article
Advertisement