Amino acid sequence of the Dank2ORF. The Dank2 protein is encoded by a 1159 amino acid residue ORF that is encoded by a 4.8 kb transcript. The cDNA sequence of the Dank2 transcript is available from GenBank under accession number AF190635. The N-terminal 24 ankyrin repeats are preceded by a 10 amino acid preankyrin segment and have been aligned below the ankyrin repeat consensus sequence. The spectrin-binding domain is encoded by 362 amino acids with an N-terminal 82 amino acid residues acidic domain, which is followed by a 280 amino acid residues basic region.