Developmental Regulation of a Local Positive Autocontrol of Supraoptic Neurons

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Fig. 1.
Fig. 1.

The spontaneous electrical activity of SON neurons is dependent on endogenous peptides release. a, Application of the OT antagonist (dOVT; 100 nm) on a tonic neuron (P16) reversibly hyperpolarized the membrane and suppressed the electrical activity. b, Application of V1a and V2 antagonists (SR 49059 and SR 121463A; 10 nm) on a phasic neuron (P15) also hyperpolarized the membrane and suppressed reversibly the electrical activity.

  1. The Journal of Neuroscience vol. 20 no. 15 5813-5819
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