
Correlation between BBB locomotor score and the number of retrogradely labeled red nuclei. Rats were actively immunized with MBP, and this was followed 1 week later by contusion. Two months after injury, a dye was applied below the primary contusion site. Five days later, the rats were killed, and their brains were excised and analyzed. A, Bar graphs show the number of labeled rubrospinal neurons in contused rats immunized with MBP in IFA or injected with PBS in IFA. B, Correlation between BBB locomotor score and the number of retrogradely labeled rubrospinal neurons. The graph shows the number of labeled neurons and the BBB score for each rat. The data for all of the examined rats are included.




