Passive or Active Immunization with Myelin Basic Protein Promotes Recovery from Spinal Cord Contusion

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Fig. 6.
Fig. 6.

Correlation between BBB locomotor score and the number of retrogradely labeled red nuclei. Rats were actively immunized with MBP, and this was followed 1 week later by contusion. Two months after injury, a dye was applied below the primary contusion site. Five days later, the rats were killed, and their brains were excised and analyzed. A, Bar graphs show the number of labeled rubrospinal neurons in contused rats immunized with MBP in IFA or injected with PBS in IFA. B, Correlation between BBB locomotor score and the number of retrogradely labeled rubrospinal neurons. The graph shows the number of labeled neurons and the BBB score for each rat. The data for all of the examined rats are included.

  1. The Journal of Neuroscience vol. 20 no. 17 6421-6430
Responses to This Article
Be the first to respond to this article
Advertisement