Passive or Active Immunization with Myelin Basic Protein Promotes Recovery from Spinal Cord Contusion

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Fig. 8.
Fig. 8.

Phase microscopy and histochemical staining of contused spinal cords. Rats were subjected to spinal cord contusion (T7) and were treated immediately with anti-MBP T cells or with PBS. After 5 months, the spinal cords from three PBS-treated controls and three anti-MBP T cell-treated rats were excised and processed for confocal microscopy. Representative micrographs from each group are shown. Note the large gap and the cysts in the neural tissues of a PBS-treated rat (a) compared with an anti-MBP T cell-treated rat (b). For comparison, a phase micrograph of a sham-operated spinal cord is included (c).

  1. The Journal of Neuroscience vol. 20 no. 17 6421-6430
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