Expectation of Pain Enhances Responses to Nonpainful Somatosensory Stimulation in the Anterior Cingulate Cortex and Parietal Operculum/Posterior Insula: an Event-Related Functional Magnetic Resonance Imaging Study

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Fig. 3.
Fig. 3.

Subjective evaluation of nonpainful warm stimulus in uncertain condition (NPS-u) and nonpainful warm stimulus in certain condition (NPS-c). Scores of individual subjects and mean scores across all subjects are shown. Diagonal line indicates equal scores for NPS-u and NPS-c conditions. Subjects rated intensity and unpleasantness of each stimulus separately. The unpleasantness score of NPS-u was significantly higher than that of NPS-c, whereas the intensity scores did not show a significant difference between the two conditions. Statistical analysis was conducted with Wilcoxon signed rank tests.

  1. The Journal of Neuroscience vol. 20 no. 19 7438-7445
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