Motivational Effects of Ethanol in DARPP-32 Knock-Out Mice

Table 2.

Mean (±SEM) grams per kilogram ethanol presented per session during each experimental phase

Experimental phase Mean gm/kg ethanol per session
KO WT
Phase 1
 Trials
  1–4 2.4  (0.2) 4.0  (0.6)
  5–8 2.0  (0.2) 3.1  (0.7)
  9–12 2.0  (0.4) 3.3  (0.7)
  13–16 2.2  (0.5) 4.0  (0.7)
  17–20 2.4  (0.4) 4.3  (0.8)
Phase 2
 Ethanol (% v/v)
  5 1.2  (0.2) 1.8  (0.4)
  10 2.6  (0.6) 4.1  (0.8)
  20 4.8  (1.0) 9.9  (1.3)
  30 6.8  (0.7) 12.1  (1.8)
Phase 3
 Ethanol (% v/v)
  5 4.5  (0.6) 7.4  (1.0)
  10 9.8  (1.1) 13.8  (1.5)
  20 15.1  (1.7) 22.4  (3.8)
  1. The Journal of Neuroscience vol. 21 no. 1 340-348
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