Motivational Effects of Ethanol in DARPP-32 Knock-Out Mice

Table 4.

Mean (±SEM) number of prandial and nonprandial fluid lever bouts during each experimental phase

Experimental phase Prandial Nonprandial
KO WT KO WT
Phase 1
 Trials
  1–4 1.2  (0.2) 1.8  (0.3) 1.1  (0.2) 2.6  (0.7)
  5–8 1.0  (0.4) 2.3  (0.7) 1.1  (0.4) 1.8  (0.7)
  9–12 1.3  (0.4) 2.6  (0.7) 1.1  (0.6) 2.4  (0.9)
  13–16 2.1  (0.7) 3.9  (0.7) 1.4  (0.7) 3.5  (1.4)
  17–20 2.3  (0.7) 4.5  (1.1) 1.6  (0.6) 3.5  (1.2)
Phase 2
 Ethanol (% v/v)
  0 1.5  (0.3) 2.6  (0.6) 0.9  (0.4) 1.2  (0.3)
  5 2.3  (0.6) 3.7  (1.1) 1.5  (0.7) 2.5  (0.8)
  10 2.4  (0.7) 4.2  (1.0) 1.8  (0.8) 3.4  (1.2)
  20 2.2  (0.6) 6.0  (1.0) 1.1  (0.5) 3.6  (0.8)
  30 2.7  (0.5) 4.7  (0.6) 1.1  (0.4) 3.0  (0.8)
Phase 3
 Ethanol (% v/v)
  0 14.1  (4.1) 13.9  (2.2) 6.3  (0.8) 14.4  (3.2)
  5 11.3  (1.0) 16.2  (1.9) 8.8  (1.2) 15.7  (2.1)
  10 11.4  (0.9) 14.8  (2.1) 8.5  (0.8) 15.6  (2.5)
  20 9.6  (1.3) 13.4  (1.6) 5.9  (1.2) 10.3  (2.4)
  1. The Journal of Neuroscience vol. 21 no. 1 340-348
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