Brain-Derived Neurotrophic Factor Increases in the Uninjured Dorsal Root Ganglion Neurons in Selective Spinal Nerve Ligation Model

Table 3.

Local application of anti-NGF antibody failed to prevent the increase in BDNF mRNA expression in the ipsilateral L4 DRG after L5 spinal nerve ligation

Ipsilateral L4 DRG
Anti-NGF Normal sheep IgG
3 POD 14.6  ± 2.5% 14.7  ± 2.1%
7 POD 10.6  ± 1.2% 12.2  ± 1.2%
  • There was no significance between the anti-NGF group and normal sheep IgG group. Mean ± SE; n = 4.

  • POD, Postoperative days.

  1. The Journal of Neuroscience vol. 21 no. 13 4891-4900
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