Distinct Changes in Cortical Acetylcholine and Noradrenaline Efflux during Contingent and Noncontingent Performance of a Visual Attentional Task

Table 2.

Basal noradrenaline and acetylcholine efflux in the prefrontal cortex of response contingent and response noncontingent subjects, measured over 2 consecutive days on the five-choice task

Contingent subjects Noncontingent subjects Group Day Time
Day 1 Day 2 Day 1 Day 2
NA 5.21  ± 0.57 5.49  ± 0.53 5.10  ± 0.53 5.04  ± 0.52 F(1,18) = 0.22;p = 0.65 F(1,18) = 0.05;p = 0.82 F(2,36) = 0.64;p = 0.53
ACh 244.9  ± 26.8 219.7  ± 29.2 256.9  ± 43.3 210.1  ± 26.7 F(1,18) = 0.01;p = 0.95 F(1,18) = 1.64;p = 0.22 F(2,36) = 0.28;p = 0.76
  • The data were averaged from the last three samples collected before task onset (expressed as fmol/10 min ± SEM;n = 10). ANOVA results for between (group)- and within (day, time)-subject effects are shown for each neurotransmitter.

  1. The Journal of Neuroscience vol. 21 no. 13 4908-4914
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