Visual Transmission Deficits in Mice with Targeted Disruption of the Gap Junction Gene Connexin36

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Fig. 7.
Fig. 7.

VEP recordings. A, Example for a VEP of a wild-type mouse in response to a 10 msec white light flash.B, Intensity–response curves were identical for wild-type (open symbols) and mutant (filled symbols) mice. Data points plot mean ± SEM (n = 5). C, Time-to-peak versus intensity curves of the VEP. Time-to-peak was significantly longer for mutant mice at the two lowest intensities used (Mann–Whitney U test; *p < 0.05; **p < 0.01; n = 5 for each data point). D, VEP examples of Cx36 +/+ and Cx36 −/− mice in response to 800-msec-long light flashes both showed ON and OFF components. Corneal illuminance was 784 lux in A andD.

  1. The Journal of Neuroscience vol. 21 no. 16 6036-6044
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