IPSC Kinetics at Identified GABAergic and Mixed GABAergic and Glycinergic Synapses onto Cerebellar Golgi Cells

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Fig. 7.
Fig. 7.

Variability and coregulation of S-IPSC and L-IPSC decay kinetics. IPSCs were averaged during the control period and during application of serotonin. L-IPSCs were distinguished by their large amplitude. A, Example of averaged S-IPSCs (left; dotted lines) and L-IPSCs (right; solid lines) recorded from two Golgi cells is shown. B, S-IPSCs, as well as L-IPSCs, of cell 1 and cell 2 were scaled and superimposed. Both were faster in cell 1 than in cell 2. C, Plot of the half decay time of the S-IPSCs recorded from 26 Golgi cells against the age of the animals is shown. D, S-IPSCs and L-IPSCs were scaled in cell 1 and in cell 2. L-IPSCs are slower than are S-IPSCs in the same proportion in both cells. E, The half decay times of L-IPSCs measured in 12 Golgi cells are plotted against the half decay times of S-IPSCs in the same cells. The solid linerepresents the linear regression through the points. Its slope is 1.28. The dashed line indicates a slope of 1. L, L-IPSC; PN, Postnatal;S, S-IPSC.

  1. The Journal of Neuroscience vol. 21 no. 16 6045-6057
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