CNS Distribution of Members of the Two-Pore-Domain (KCNK) Potassium Channel Family

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Fig. 3.
Fig. 3.

TASK-1 and TASK-3 show high levels of mRNA accumulation in the locus ceruleus; TWIK-1 is highly expressed by adjacent mesencephalic trigeminal neurons. Panels show dark-field images of coronal sections through the dorsolateral pons corresponding to autoradiograms in Figure 1D. Arrowheads in each panel mark the approximate boundary of the locus ceruleus, which had high levels of labeling for TASK-1 (A) and was even more densely labeled for TASK-3 (B). Large mesencephalic trigeminal neurons are located lateral to the locus ceruleus; these neurons showed high levels of TWIK-1 (arrow in C). Scale bar, 300 μm.

  1. The Journal of Neuroscience vol. 21 no. 19 7491-7505
Responses to This Article
Be the first to respond to this article
Advertisement