Effects of intracerebral injection of saline, LY367385 (20 nmol), LY367366 (20 nmol), mGlu1, or mGlu5 antisense oligonucleotides (ASm1 or ASm5, 12 nmol) or a scrambled oligonucleotide (SCRm5, 12 nmol) on the width of molecular layer and granule cell number in the cerebellar cortex. The control bar refers to values obtained from noninjected animals. Measurements were taken from the preculminate fissure in the anterior cerebellum. Values are means ± SEM of three to five animals per group. *p < 0.05 (one-way ANOVA + Fisher's PLSD) versus control or saline.