Table 1.
Effect of MPEP or CPCCOEt treatment on Purkinje cell dendrites in culture
| Total length of the dendritic tree (μm) | Number of dendritic branches | Diameter of primary dendrites | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 9 DIV | 13 DIV | 17 DIV | 9 DIV | 13 DIV | 17 DIV | 9 DIV | 13 DIV | 17 DIV | |
| Control | 1173 ± 86 | 2757 ± 298 | 3707 ± 453 | 59 ± 3 | 117 ± 12 | 104 ± 7 | 7.41 ± 0.2 | 5.35 ± 0.2 | 6.24 ± 0.2 |
| (n = 12) | (n = 19) | (n = 7) | (n = 12) | (n = 10) | (n = 7) | (n = 79) | (n = 31) | (n = 26) | |
| MPEP | 831 ± 44* | 1470 ± 133* | 4390 ± 499 | 40 ± 2* | 44 ± 5* | 118 ± 10 | 5.96 ± 0.2* | 4.02 ± 0.1* | 5.06 ± 0.2* |
| (n = 10) | (n = 11) | (n = 7) | (n = 10) | (n = 11) | (n = 7) | (n = 51) | (n = 50) | (n = 24) | |
| CPCCOEt | 781 ± 59* | 2823 ± 361 | 4408 ± 238 | 33 ± 1* | 97 ± 6 | 96 ± 4 | 7.16 ± 0.2 | 5.61 ± 0.2 | 5.654 ± 0.1 |
| (n = 13) | (n = 13) | (n = 7) | (n = 13) | (n = 13) | (n = 7) | (n = 68) | (n = 37) | (n = 37) | |
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Data represent mean ± SEM.
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↵* p < 0.05 (one-way ANOVA + Fisher's PLSD). n, Number of Purkinje cells analyzed. Cells were chosen randomly from three dishes, each from a different experiment.
