Tangential migration of a granule cell in the middle level of the EGL. A, During the observation period, the granule cell soma (white asterisks) gradually moved toward the left side of the cerebellar hemisphere at a rate of 18.8 μm/hr. The distal portion of the leading process had large motile lamellipodia (small white arrowheads). Time interval (in minutes) is indicated on the top right of each photograph. Scale bar, 10 μm. The total distance traversed by the granule cell soma (B), the direction and distance traveled by the soma during each 10 min of the testing period (C), the length/width ratio of the soma (D), and the leading process length (E) were plotted as a function of elapsed time. In C, positive values represent forward cell movement, and negative values represent backward cell movement.