
Urodynamic analysis of detrusor–EUS coordination in representative uninjured (A, D, G, J), 12.5 mm SCI (B, E, H, K), and 50 mm SCI (C, F, I, L) animals. A–C, Bladder intravesical pressure (IVP) recordings during one voiding cycle. Solid horizontal lines in A and Bindicate the duration of stream-like voiding, and the dashed line in C indicates the drop-by-drop voiding.D–F, EUS EMG recordings, showing an activation of EUS EMG in relationship to the voiding cycle in uninjured and 12.5 mm SCI animals but not in the 50 mm SCI animal. G–I, Power spectrum analysis of EUS EMG activity as a function of time. A broad band of frequencies (5–40 Hz) shows an increased power during the voiding phase in uninjured and 12.5 mm SCI animals but not in the 50 mm SCI animal. J–L, Peak detection analysis of the ESA. Peaks were detected in 1 dsec intervals. An increase in ESA (dESA) occurred at the time corresponding to the voiding phase in uninjured and 12.5 mm SCI animals, but there was no change in the level of ESA in the 50 mm SCI animal.




