Changes in LUT parameters after SCI
| Parameter | SCI (mm) | |||
|---|---|---|---|---|
| 0 (n = 6) | 12.5 (n = 7) | 25 (n = 4) | 50 (n = 7) | |
| Spontaneous voiding (dpi) | 0.0 ± 0.0 | 2.5* ± 1.8 | 4.3* ± 1.0 | 4.4** ± 0.9 |
| Bladder weight (gm) | 0.11 ± 0.01 | 0.23 ± 0.09 | 0.37* ± 0.13 | 0.41* ± 0.18 |
| Bladder volume (ml) | 3.8 ± 1.5 | 9.1 ± 6.0 | 14.9* ± 6.2 | 26.1** ± 8.1 |
| Amplitude (mmHg) | 25.4 ± 7.7 | 19.4 ± 7.6 | 14.1 ± 3.0 | 13.0* ± 5.1 |
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The number of animals in each group is shown in parentheses. Spontaneous voiding was calculated as the number of days postinjury (dpi) when the volume of manually expressed urine first began to decrease. Urodynamic evaluation was performed at 8 weeks after surgery in SCI (12.5, 25, and 50 mm) and uninjured (0 mm) groups. The bladder was then weighed after blot-drying, and its length and width were measured to calculate the volume. The amplitude of bladder pressure was calculated as the difference between the maximal intravesical pressure during voiding and the pressure just before the voiding was initiated (threshold pressure). There was a significant difference among the SCI groups as calculated by ANOVA (p = 0.01), with Tukey'spost hoc test indicating the significant difference (p < 0.05) from the uninjured group (one asterisk) or from the uninjured and 12.5 mm groups (two asterisks).
