Table 2.
Expression of NMDA (NR1, NR2A, and NR2B) and AMPA (GluR1, GluR2, GluR3, and GluR4) subunit mRNA in DL motoneurons at 8 weeks
| Subunit | SCI (mm) | |||
|---|---|---|---|---|
| 0 (n = 6) | 12.5 (n = 7) | 25 (n = 3) | 50 (n = 5) | |
| NR1 | 39.4 ± 8.7 | 43.7 ± 6.0 | 43.1 ± 6.4 | 45.1 ± 5.3 |
| NR2A | 6.8 ± 1.5 | 9.9 ± 2.7 | 12.4* ± 4.1 | 12.3* ± 2.9 |
| NR2B | 1.6 ± 0.4 | 2.3 ± 0.5 | 2.2 ± 0.5 | 2.2 ± 0.2 |
| GluR1 | 1.3 ± 0.2 | 1.6 ± 0.5 | 1.6 ± 0.4 | 2.0 ± 0.6 |
| GluR2 | 4.6 ± 1.1 | 6.3 ± 2.2 | 10.5* ± 1.6 | 8.2* ± 2.6 |
| GluR3 | 3.2 ± 2.1 | 5.8 ± 1.3 | 4.9 ± 1.6 | 5.9 ± 2.6 |
| GluR4 | 2.4 ± 0.6 | 2.9 ± 0.6 | 2.0 ± 0.3 | 2.3 ± 0.2 |
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The data are presented as the number of grains per square micrometer of cell area. Significant difference from the uninjured group is indicated by an asterisk and is based on p < 0.05 in Tukey's post hoc test after ANOVA.
