Structural Determinants of Fast Desensitization and Desensitization–Deactivation Coupling in GABAAReceptors

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Fig. 6.
Fig. 6.

The effect of YF to VY mutation in the α1 or β3 subunits of αβγ receptors. α1(YFΔVY) was coexpressed with β3 and γ2L, and β3(YFΔVY) was coexpressed with α1 and γ2L. The middle column illustrates representative currents. Bar graphs are as in Figure 2. Theasterisks indicates significant difference (p < 0.05) from both αβδ and αβγ receptors. Horizontal calibration: 400 msec; vertical calibration: 150 pA for α1(YFΔVY), and 116 pA for β3(YFΔVY).

  1. The Journal of Neuroscience vol. 21 no. 4 1127-1136
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