Rapid Signaling at Inhibitory Synapses in a Dentate Gyrus Interneuron Network

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Fig. 1.
Fig. 1.

Fast unitary IPSCs in synaptically connected BC–BC pairs. A, Presynaptic action potential (top), single unitary IPSCs (6 sweeps superimposed,center), and average IPSC (from 38 sweeps,bottom) at −70 mV are depicted. The schematic illustration on top illustrates the recording configuration. B, Histograms of latencies, 20–80% rise times, peak amplitudes of average unitary IPSCs (including failures), and decay time constants [amplitude-weighted mean decay time constant τw (biexponential fit) in 11 pairs and τm(monoexponential fit) in 3 pairs]. Values of latencies, rise times, amplitudes, and decay time constants were determined from average IPSCs (including >10 individual traces). For latency measurements, one pair was excluded because of high presynaptic series resistance. Shown are summary graphs of data from 14 rigorously identified BC–BC pairs.

  1. The Journal of Neuroscience vol. 21 no. 8 2687-2698
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