Table 1.
Basic properties of PF-EPSCs in mutant mice
| Amplitude (pA) | Decay time constant (msec) | 10–90% Rise time (msec) | Paired-pulse ratio (%) | |
|---|---|---|---|---|
| Mice (P14–20) | ||||
| wt | 272.6 ± 30.4 (14) | 12.1 ± 1.3 (14) | 1.82 ± 0.16 (10) | 165.3 ± 7.9 (11) |
| tg | 168.3 ± 26.4* (14) | 12.0 ± 0.8 (14) | 2.26 ± 0.21 (10) | 181.9 ± 6.0 (10) |
| tgrol | 79.6 ± 11.7* (10) | 12.9 ± 1.6 (10) | 2.44 ± 0.34 (10) | 212.8 ± 18.7* (10) |
| Mice (P28–32) | ||||
| wt | 319.4 ± 21.3 (10) | 12.4 ± 1.4 (10) | 2.08 ± 0.29 (10) | 158.9 ± 4.5 (10) |
| tg | 88.76 ± 46.3 (10) | 13.0 ± 2.3 (10) | 2.22 ± 0.52 (10) | 159.6 ± 9.7 (10) |
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PF-EPSCs were evoked by 10 V stimulation. All data are expressed as mean ± SEM. Numbers of recorded Purkinje cells are shown in the parentheses. The decay time constant was obtained by fitting the EPSC decay with a single exponential. Paired-pulse ratio is second EPSC/first EPSC. Interpulse interval is 50 msec.
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↵* p < 0.05.
