Light microscopic image of lingual tissue from an adult male H253 mouse treated with Simvistatin. Tissue was sectioned, stained with X-gal, and then counterstained with nuclear fast red. Blue, nuclear precipitate indicates β-gal activity. Basal cells in nontaste bud-bearing epithelium lack X-gal staining (arrow), as do perigemmal cells surrounding the taste bud (arrowhead). Scale bar, 20 μm.