Biochemical Engineering of Cell Surface Sialic Acids Stimulates Axonal Growth

Table 2.

Proteins identified by MALDI-TOF MS

Protein Species MW Theoretical MW PI Theoretical PI Number of matched peptides % sequence coverage Upregulation/downregulation
α enolase Rat 48000 49984 6.5 6.16 13 35.8 Downregulation
ULIP protein Mouse 60000 61936 6.3 6.04 9 20.4 Downregulation
Tyrosine-3-monooxygenase Rat 59000 55966 5.8 5.74 18 51.6 Downregulation
Heat shock cognate protein 71 Rat 70000 70804 5.4 5.24 15 31.7 Downregulation
Farnesyl pyrophosphate synthetase Rat 35000 40829 5.5 5.9 16 39.1 Downregulation
14-3-3 protein ε Rat 27000 29173 4.5 4.63 13 53.7 Downregulation
Ubiquitin C-terminal hydrolase isozyme L1 Rat 23000 24782 5.4 5.12 8 45.7 Downregulation
Tropomyosin 5 Mouse 27000 29020 4.8 4.75 16 59.7 Downregulation
Heat shock 27 kDa protein Rat 22000 22892 6.1 6.12 13 56.8 Upregulation
Aldose reductase Rat 34000 35666 6.5 6.28 10 49.5 Downregulation
  • MW, Molecular weight; PI, isoelectric point.

  1. The Journal of Neuroscience vol. 22 no. 20 8869-8875
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