A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding

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Fig. 3.
Fig. 3.

A, Capsaicin treatment abolished the anorexic effect of CCK-8, which acts peripherally, but not that of the 5-HT-1B agonist CP93129, which acts centrally.B, WIN55,212-2 (WIN) did not produce hyperphagia in capsaicin-treated rats. C, Capsaicin treatment abolished the reduction of food intake elicited by SR141716A (SR) in food-deprived rats.VEH, Vehicle. Data are the means ± SEM of at least 10 determinations per group. *p < 0.01 versus vehicle-treated group; Newman–Keuls.

  1. The Journal of Neuroscience vol. 22 no. 21 9612-9617
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