
A, Capsaicin treatment abolished the anorexic effect of CCK-8, which acts peripherally, but not that of the 5-HT-1B agonist CP93129, which acts centrally.B, WIN55,212-2 (WIN) did not produce hyperphagia in capsaicin-treated rats. C, Capsaicin treatment abolished the reduction of food intake elicited by SR141716A (SR) in food-deprived rats.VEH, Vehicle. Data are the means ± SEM of at least 10 determinations per group. *p < 0.01 versus vehicle-treated group; Newman–Keuls.




