The Cytokine Network of Wallerian Degeneration: Tumor Necrosis Factor-α, Interleukin-1α, and Interleukin-1β

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Fig. 7.
Fig. 7.

TNFα, IL-1α, and IL-1β protein are detected in injury domains but not slow-WD domains of Wld mice 3 d after injury. The PNS segment, which is situated distal to the injury site, was removed 3 d after injury, and cryostat sections were taken from the injury domain and its mate slow-WD domain. These were then processed simultaneously side by side for the detection of TNFα, IL-1α, and IL-1β protein by immunofluorescence microscopy. Magnification: 250×.

  1. The Journal of Neuroscience vol. 22 no. 8 3052-3060
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