Ultrastructural analysis of LMP7-positive neurons from the cortex of HD patients. Immunoelectronmicroscopy images of cortical section from control (A) or HD human samples (B) stained with LMP7. A, Neuron with cytoplasmic LMP7 staining in the cortex of control subject. B, Nuclear indentations (empty arrows) in LMP7-positive cortical neurons from HD cases. Black arrows, Patches of reaction product. Arrowheads, Lipofuscin accumulations. Scale bar, 1 μm.