Distinct Developmental Modes and Lesion-Induced Reactions of Dendrites of Two Classes of Drosophila Sensory Neurons

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Fig. 7.
Fig. 7.

Loss of one of the two ddaC terminals, coming close to each other, triggered ingrowth of the other one.A–C, Dorsal clusters in larvae of NP7028 GFP[S65T]/GFP[S65T] just after hatching (20–25 hr AEL). Each green arrow indicates a dendrodendritic contact (A) or a pair of terminals that were getting close to each other (B, C). Yellow arrows represent proximal dendritic roots that were severed.D–F, Images of 16–20 hr after severing of the roots as pointed in A–C, respectively. G–I, Tracings of dendrites of injured neurons (black), those of ipsilateral homologs (green), and those of contralateral ones (purple). The remaining terminals of either ipsilateral or contralateral homologs invaded territories that were normally covered by the detached branches (yellow arrowheads in D, E, G, andH and brackets in F and I). Isoneuronal branches in A and B filled in voided fields as shown in D and E, respectively (blue arrowheads), and some of them covered bounds of the neutral zones (purple arrowheads in D and F). Brackets inD and E indicate the neutral zones. At 31–33 hr AEL between B and E, we confirmed that the branch, which was targeted at 23–25 hr AEL (yellow arrow inB), was actually destroyed (data not shown). Scale bars:A–C, 20 μm; D–F, 50 μm.

  1. The Journal of Neuroscience vol. 23 no. 9 3752-3760
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