Figure 4.
Effect of 5,7-DHT lesion (a, b) or (±)-8-OH-DPAT administration (c, d) on SB 206553-induced DA release in the striatum and the nucleus accumbens. SB 206553 (5 mg/kg, i.p.) was administered alone (a, b) or 5 min after the subcutaneous injection of the 5-HT1A agonist 8-OH-DPAT (DPAT; 0.1 mg/kg) (c, d) (vertical arrows). Data represent mean ± SEM percentages of baseline (n = 4–6 animals/group).
