Switching Mature Retinal Ganglion Cells to a Robust Growth State In Vivo: Gene Expression and Synergy with RhoA Inactivation

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  Figure 1.
Figure 1.

RGCs go into a regenerative state 4 d after axotomy accompanied by lens injury. a-c, Retinal explants from mature rats after 48 hr in culture. Retinas were subjected to no previous treatment (a), axotomy alone 4 d before explanting (b), or axotomy plus lens injury 4 d beforehand (c). d, Quantitation of results: axons per explant after 24 or 48 hr in culture. Data represent results from normal retinas (0) or from retinas subjected to axotomy (Axot), with or without lens injury, 1-7 d beforehand, as indicated.

  1. The Journal of Neuroscience vol. 24 no. 40 8726-8740
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