Physiological and Morphological Characterization of Dentate Granule Cells in the p35 Knock-Out Mouse Hippocampus: Evidence for an Epileptic Circuit

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  Figure 4.
Figure 4.

Intrinsic GC properties are similar in wild-type and knock-out dentate. A, A representative family of voltage responses to step current injections (from -0.5 to +0.5 nA; steps shown in inset) from a wild-type and a knock-out GC. Calibration: 10 mV (vertical), 25 msec (horizontal); inset, 0.2 nA (vertical), 25 msec (horizontal). B, Plots of the current-voltage relationship for the cells presented in A. C, Plots of the number of action potentials elicited at given current step amplitudes. Each point shows mean ± SEM for 20 cells in the wild-type and knock-out groups.

  1. The Journal of Neuroscience vol. 24 no. 41 9005-9014
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