Supplemental data

Files in this Data Supplement:

• Adobe PDF - Supplementary_methods.pdf
• supplemental material - Supplementary figure 1 Measured parameters for the evaluation of synaptic plasticity in a representative experiment (a) Time course of EPSP slope. (b) Time course of EPSP amplitude. (c) Time course of EPSP area under the curve. (d) Time course of EPSP time to peak.
• supplemental material - Supplementary figure 2 Synaptic modifications following step pulse pairing Gray window: schematic illustration of step pulse pairing configuration. (a) Coincident pairing configuration: EPSPs (top) coincide with the step pulse-induced APs (bottom). (b) Antiphase pairing configuration: EPSPs (top) are in antiphase with the step pulse-induced APs (bottom). (c) 20Hz step pairing in control ACSF. (d) 20Hz step pairing in the presence of carbachol. (e)-(f) Time-course of EPSP amplitude changes (grand averages) with 20Hz step pairing in control ACSF (c) and in the presence of carbachol (d). Triangles: Coincident pairing; Circles: Antiphase pairing.