Ethanol increases presynaptic GABA_B receptor function. A, Representative time course illustrating the effect of 1.25 μm baclofen (BAC) in the absence and presence of 80 mm ethanol (EtOH) on the area of proximal GABA_A IPSCs. Responses were pharmacologically isolated as in Figure 1. Traces above the graph are averages of six to eight IPSCs evoked at the times indicated by the corresponding letters. B, Bar graph summarizing the effect of 1.25 μm BAC on proximal GABA_A IPSCs when applied alone or in the presence of 20, 40, or 80 mm EtOH or 1 μm FLU. ^*p < 0.05, relative to BAC alone, post hoc Neuman-Keuls test. Numbers in parentheses represent the number of cells tested under each experimental condition.