Ethanol does not potentiate postsynaptic GABA_B receptor function in rat CA1 pyramidal neurons. A, Representative traces illustrating the effect of 80 mm ethanol (EtOH) and 20 μm SCH 50911 on the area of GABA_B IPSCs evoked by stimulation of the stratum lacunosummoleculare in the presence of APV, DNQX, and 20 μm bicuculline methiodide. Traces are averages of five GABA_B IPSCs recorded under the conditions indicated. The bar graph summarizes the effect of EtOH and SCH 50911 on the area of GABA_B IPSCs. CTL, Control; WASH, washout. B, Representative time course of the outward current generated by bath application of 20 μm baclofen (BAC) in the absence and presence of 80 mm EtOH. The bar graph summarizes the maximal amplitude of BAC-evoked currents recorded in the absence and presence of EtOH. Numbers in parentheses represent the number of cells tested under each experimental condition.