Open-field test on Ad-1AP-antisense-injected mice. Data are presented as mean ± SEM for 14-21 mice. One-way ANOVA for horizontal activity: F_(1,33) = 5.4, p = 0.03; for vertical activity: F_(1,33) = 11.8, p = 0.0016; for margin time: F_(1,33) = 0.88, p = 0.36. ^*Significant difference from Ad-track-injected mice (p < 0.05) by Student-Newman-Keuls post hoc test.