Inhibition of Conditioned Stimulus Pathway Phosphoprotein 24 Expression Blocks the Reduction in A-Type Transient K+ Current Produced by One-Trial In Vitro Conditioning of Hermissenda

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  Figure 5.
Figure 5.

Csp antisense incubation blocked the reduction in IA produced by one-trial conditioning. A, Exemplary IA current traces elicited from a holding potential of -80 mV to step potentials ranging from -80 to + 40 mV with ΔV = 10 mV. B, Similar current traces elicited from an antisense-treated conditioned type B photoreceptor. C, Group summary data in current density-voltage plot of IA from the normal control group (n = 7) and groups examined 1.5 h (n = 7), 3.5 h (n = 7), and 16 h (n = 7) after one-trial conditioning. All conditioned groups were incubated in the antisense oligonucleotide. There were no statistically significant changes in the current densities in antisense-treated B cells measured at the different times after conditioning relative to the control group. Error bars represent SD.

  1. The Journal of Neuroscience vol. 25 no. 19 4793-4800
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