Uptake and Neuritic Transport of Scrapie Prion Protein Coincident with Infection of Neuronal Cells

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  Figure 6.
Figure 6.

m(Ch)PrP-resA568-labeled vesicles do not colocalize with GFP-Vacht, a synaptic vesicle marker. a, m(Ch)PrP-resA568 distribution in the cytosol. b, GFP-Vacht accumulates in a perinuclear region and neuritic processes. c, Merged image (GFP-Vacht, green; m(Ch)PrP-resA568, red). d, e, Magnifications of the merged images of neuritic processes (d, e) in c. Images are consistent with 26 cells in four independent experiments. Scale bars, 20 μm.

  1. The Journal of Neuroscience vol. 25 no. 21 5207-5216
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