Kainate receptors mediate quantal events independently from AMPA receptors at the same population of inputs on to the same cells. A, Example averaged eEPSC (in 2.5 mm Ca²⁺, 0 mm Sr²⁺). Data in A-E are from the same cell. B, Example individual traces in the presence of Sr²⁺ (0 mm Ca²⁺, 2 mm EGTA) showing the eEPSC followed by evoked mEPSC_slow (indicated by arrows). C, Averaged mEPSC_slow and single-exponential fit of the decay (gray). D, Example individual traces in the presence of Sr²⁺ (0 mm Ca²⁺, 2 mm EGTA) showing the eEPSC followed by evoked mEPSC_fast (indicated by asterisks; note that both mEPSC_fast and mEPSC_slow events are evident in the bottom trace). E, Averaged mEPSC_fast and single-exponential fit to the decay (gray). F, Averaged eEPSC_slow and single-exponential fit to the decay (gray). G, Values for 10-90% rise time: left, mEPSC_fast (n = 42), eEPSC (n = 42); and right, mEPSC_slow (n = 10) and eEPSC_slow (n = 10). H, τ_decay values: left, mEPSC_fast (n = 42) and the fast component of eEPSC (n = 42); right, mEPSC_slow (n = 6), eEPSC_slow (n = 9), and the slow component of eEPSC (n = 29). I, Summary data of the mean quantal amplitude (Q) of AMPA (n = 42) and kainate (n = 13) receptor-mediated evoked mESPCs. J, Summary data for the mean charge carried by the two types of evoked mEPSCs (AMPA, n = 42; kainate, n = 6).