Developmental Changes in AMPA and Kainate Receptor-Mediated Quantal Transmission at Thalamocortical Synapses in the Barrel Cortex

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  Figure 8.
Figure 8.

Summary of single-channel properties of AMPA receptors at developing thalamocortical synapses. A, mEPSCfast 10-90% rise time plotted versus γ for all cells (n = 35). B, mEPSCfastτdecay plotted versus γ for all cells (n = 35). The line is a linear regression, and τdecay is weakly but significantly correlated with γ (r = 0.389; p < 0.05). C, mEPSCfast amplitude plotted versus γ for all cells (n = 35). D, Estimated number of channels contributing to mEPSCfast plotted versus γ for all cells (n = 35). The line is a fit to the data of the following form: number of channels = Q/γ× 0.07, iterated with Q as the free parameter; Q = 1 0.3 ± 0.45 pA; r2 = 0.94. The number of channels is significantly correlated with γ (p < 0.0001).

  1. The Journal of Neuroscience vol. 25 no. 21 5259-5271
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