Developmental Changes in AMPA and Kainate Receptor-Mediated Quantal Transmission at Thalamocortical Synapses in the Barrel Cortex

Table 3.

Average characteristics of stochastic AMPA and kainate receptors simulated with the Monte Carlo technique

AMPA Kainate
k+1 (m/s) 2.66 × 107 2.66 × 107
k−1 (s−1) 6.24 × 103 6.24 × 103/250
k+2 (m/s) 1.33 × 107 1.33 × 107
k−2 (s−1) 1.25 × 104 1.25 × 104/250
k+3 (M/s1) 1.33 × 107 0.00001
k−3 (s−1) 6.24 × 103 0.00001
α (s−1) 5.7 × 103 1.0 × 103
β (s−1) 8.0 × 102 4.0 × 102
α1 (s−1) 20.0 0.00001
β1 (s−1) 361.0 0.00001
α2 (s−1) 18.0 0.00001
β2 (s−1) 650.0 0.00001
α3 (s−1) 3.0 × 103 3.0 × 103
β3 (s−1) 1.0 × 103 1.0 × 103
10-90% rise time (msec) 0.28 2.3
τdecay (msec) 3.0 133.0
Po,max 0.60 0.29
γ (pS) 16 6
  1. The Journal of Neuroscience vol. 25 no. 21 5259-5271
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