Urotensin II Modulates Rapid Eye Movement Sleep through Activation of Brainstem Cholinergic Neurons

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

  Figure 6.
Figure 6.

Effects of intracerebroventricular injection of 0.6 nmol of UII on the EEG power. UII induced a significant increase in the mean power of θ (A; p < 0.01) and γ (B; p < 0.01) bands during W, as well as a significant increase in γ during REM sleep (D; p < 0.01) compared with saline, whereas UII reduced the δ power in SWS2. However, this reduction did not reach significant levels (C). These results confirm the role of UII in cortical activation. Bars represent mean values (±SEM; n = 6 rats per group). Significant effects of UII compared with the saline group were identified using a t test and are indicated by asterisks.

  1. The Journal of Neuroscience vol. 25 no. 23 5465-5474
Responses to This Article
Be the first to respond to this article
Advertisement